The Effect of Resveratrol on Swarming Differentiation and the Expression of Some Virulence Factors in Proteus vulgaris

Resveratrol (3,5,4'-trihydroxy-trans-stilbene) is a stilbenoid, a type of natural phenol, and a phytoalexin with anti-inflammatory and antioxidant activities. It is produced naturally by several plants especially the roots of the Japanese Knotweed when under attack by pathogens such as bacteria or fungi. In this study we have verified that resveratrol has activity against Proteus vulgaris, an important pathogen infecting the urinary tract by investigating its effect on swarming and some virulence factor expression(haemolysin and urease).Swarming inhibition was determined on Luria Bertani agar with and without resveratrol and then bacteria was harvested to assay cell length and the production of haemolysin and urease.  Resveratrol significantly inhibited swarming and virulence factor expression but its effect on growth rate was not significant. Keywords: Resveratrol, Proteus vulgaris, phytoalexin, haemolysin, urease

Detection P53, Rb1 and H-ras Loss of Heterozygosity LOH in Patients with Urinary Bladder carcinoma

In this study 22 samples of urine sediments were obtained from patients with Urinary Bladder Carcinoma, DNA base technique and LOH detection was investigated in three genes P53, Rb1 and H-ras. The result are shown that LOH was present in most cases and for all genes where LOH in P53 represents (31.8%) and for Rb1 (45.4%) and for H-ras gene (27.2%).In some cases, more than one gene locus mutations were found

Bacteriological and immunological study associated with patients of Urinary Bladder carcinoma

The blood, serum & urine samples are collected from (22) patients with urinary bladder cancer were admitted to Al-Hilla general teaching hospital after diagnosis by helping urology physician. The result appeared that E.coli with high percentage (22.7% ,27.2%)in nixed &single infection respectively followed by Ps.aeuroginosa (22.7% , 13.6%) and S.aureus (18.8% , 9.09%).   Interleukin 2 &Interleukin 8 concentration level was detected in serum by enzyme-linked immunosorbent assay(ELISA) and data were compared with control to compare the performance of each cytokins & results show no elevated , no significant decrease in level  in two cytokins, this leads  to an independent factors for the detection of urinary bladder cancer

Prevalence of Human Monkeypox virus

ظهر جدري القرود في بلدان وسط وغرب إفريقيا. تم التعرف على نوعين متميزين ، نوع غرب أفريقيا والنوع الكونغو ، والمعروف أيضًا بنوع إفريقيا الوسطى ، تم اكتشافه لأول مرة في عام 1958 ، بينما تم تشخيص أول حالة بشرية للمرض في عام 1970 في الجمهورية من الكونغو في طفل يبلغ من العمر 7 سنوات ، وانتشر جدري القرود بشكل أساسي في دول وسط وغرب إفريقيا ، حيث تم تسجيل المرض خارج قارة إفريقيا 3 مرات فقط بحلول عام 2022 ، تم العثور على أدلة على جدري القرود في الحيوانات بما في ذلك السناجب والجرذان. تتراوح فترة الحضانة من 5-21 يومًا ، وينتقل جدرى القرود للإنسان عن طريق الاتصال بالفيروس المسبب له ؛ الفم والاتصال بالحيوانات المصابة ، بما في ذلك الفئران والجرذان والسناجب ، وهو أمر شائع لانتقال جدري القرود في إفريقيا ، أثناء عضات الحيوانات من الحيوانات المصابة إلى البشر. ملامسة فرو أو جلد الحيوانات أو ما يخرج منها من الدم أو سوائل الجسم. ينتقل الفيروس من الأم إلى الجنين. تتشابه الأعراض الرئيسية لجدري القرود مع أعراض الجدري ، لكنها أكثر اعتدالًا ، والفرق الوحيد هو تورم الغدد الليمفاوية والحمى والصداع وآلام الظهر والسعال والتهاب الحلق وانسداد الأنف والتعب والإرهاق والتعرق. يبدأ الطفح الجلدي لجدري القرود بالظهور بعد 1-3 أيام من المريض المصاب بالحمى التي تظهر على الوجه أولاً ، ثم يبدأ الجسم بالانتشار إلى باقي الأجزاء مثل اليدين والساقين وداخل الفم والأعضاء التناسلية. والملتحمة والقرنية. من مضاعفات جدري القرود عدوى بكتيرية ثانوية ، مثل الالتهاب الرئوي والتهاب الدماغ والتهاب العين.  Monkeypox virus appeared in the countries of Central and West Africa. Two distinct species have been identified, the West African type and the Congo type, also known as the Central African type.In the outbreak of monkeypox was first discovered in 1958, while the first human case of the disease was diagnosed in 1970 in the Republic of the Congo in a 7-year-old child. The incubation period ranges from 5-21 days.Monkeypox is transmitted to humans by contact with the virus that causes it through;Mouth and contact with infected animals, including mice, rats, and squirrels, common for monkeypox transmission in Africa, during animal bites from infected animals to humans. Touching the fur or skin of animals, or what comes out of them from blood or bodily fluids. In the case of monkeypox, the virus is transmitted from the mother to the fetus. The main symptoms of monkeypox are similar to the symptoms of smallpox, but they are milder, with the only difference being swollen lymph nodes, fever, headache, backache, cough, sore throat, stuffy nose, fatigue, exhaustion and sweating. The rash of monkeypox begins to appear after 1 - 3 days from the patient with fever, which appears on the face first, then the body begins to spread to the rest of the parts, such as the hands, legs, inside the mouth, genitals, conjunctiva, and the cornea. A complication of monkeypox is Secondary bacterial infection, such as pneumonia, encephalitis, and eye infection

Minimizing the sum of flow times with batching and delivery in a supply chain

The aim of this thesis is to study one of the classical scheduling objectives that is of minimizing the sum of flow times, in the context of a supply chain network. We consider the situation that a supplier schedules a set of jobs for delivery in batches to several manufacturers, who in tum have to schedule and deliver jobs in batches to several customers. The individual problem from the viewpoint of supplier and manufacturers will be considered separately. The decision problem faced by the supplier is that of minimizing the sum of flow time and delivery cost of a set of jobs to be processed on a single machine for delivery in batches to manufacturers. The problem from the viewpoint of manufacturer is similar to the supplier's problem and the only difference is that the scheduling, batching and delivery decisions made by the supplier define a release date for each job, before which the manufacturer cannot start the processing of that job. Also a combined problem in the light of cooperation between the supplier and manufacturer will be considered. The objective of the combined problem is to find the best scheduling, batching, and delivery decisions that benefit the entire system including the supplier and manufacturer. Structural properties of each problem are investigated and used to devise a branch and bound solution scheme. Computational experience shows significant improvements over existing algorithms and also shows that cooperation between a supplier and a manufacturer reduces the total system cost of up to 12.35%, while theoretically the reduction of up to 20% can be achieved for special cases.EThOS - Electronic Theses Online ServiceGBUnited Kingdo

Sequencing mixed-model assembly lines in just-in-time production systems

This thesis proposes a new simulated annealing approach to solve multiple objective sequencing problems in mixed-model assembly lines. Mixed-model assembly lines are a type of production line where a variety of product models similar in product characteristics are assembled. Such an assembly line is increasingly accepted in industry to cope with the recently observed trend of diversification of customer demands. Sequencing problems are important for an efficient use of mixed-model assembly lines. There is a rich of criteria on which to judge sequences of product models in terms of line utilization. We consider three practically important objectives: the goal of minimizing the variation of the actual production from the desired production, which is minimizing usage variation, workload smoothing in order to reduce the chance of production delays and line stoppages and minimizing total set-ups cost. A considerate line manager would like to take into account all these factors. These are important for an efficient operation of mixed-model assembly lines. They work efficiently and find good solution in a very short time, even when the size of the problem is too large. The multiple objective sequencing problems is described and its mathematical formulation is provided. Simulated annealing algorithms are designed for near or optimal solutions and find an efficiency frontier of all efficient design configurations for the problem. This approach combines the SA methodology with a specific neighborhood search, which in the case of this study is a "swapping two sequence". Two annealing methods are proposed based on this approach, which differ only in cooling and freezing schedules. This research used correlation to describe the degree of relationship between results obtained by method B and other heuristics method and also for quality of our algorithm ANOVA's of output is constructed to analyse and evaluate the accuracy of the CPU time taken to determine near or optimal solution.EThOS - Electronic Theses Online ServiceMinistry of Culture and Higher Education of the Islamic Republic of IranGBUnited Kingdo

Preceding rule induction with instance reduction methods

A new prepruning technique for rule induction is presented which applies instance reduction before rule induction. An empirical evaluation records the predictive accuracy and size of rule-sets generated from 24 datasets from the UCI Machine Learning Repository. Three instance reduction algorithms (Edited Nearest Neighbour, AllKnn and DROP5) are compared. Each one is used to reduce the size of the training set, prior to inducing a set of rules using Clark and Boswell's modification of CN2. A hybrid instance reduction algorithm (comprised of AllKnn and DROP5) is also tested. For most of the datasets, pruning the training set using ENN, AllKnn or the hybrid significantly reduces the number of rules generated by CN2, without adversely affecting the predictive performance. The hybrid achieves the highest average predictive accuracy

Molecular Study on Multidrug Resistant of Salmonella Enterica Isolated from patient with Enteric Fever in Najaf -Province/Iraq

Abstract Minimum Inhibitory concentration of four antimicrobials used in treatment o

Weight Reduction Perception and Practice among Female Students in Al-Azhar University-Gaza, Palestine

Objectives: The present study aimed to determine the frequency of weight reduction perception. Methods: A sample of 467 female students from Al-Azhar University in the Gaza Strip was selected on a convenience basis. Information obtained from the participants included: age, marital status, place of residence, employment status, health status, methods of weight reduction, sources of information about weight control, and current physical activities. Results: The present study found that 38.8% of female students had practiced weight reduction. The most prevailing attitudes for reducing weight described by the students was sports with 83.3%, followed by exclusion of some principal meals or principal nutrients (57.8%). It was found that 38.5% of the students did not practice any physical exercise. An inverse association was also present between the satisfaction about body weight and the practice of weight reduction